Jessner’s lymphocytic infiltrate (JLI), also called benign lymphocytic infiltration of the skin, is a rare, benign dermatosis with a self-limiting course and an excellent prognosis. It typically presents as erythematous papules and plaques primarily located on the face, neck, or upper back.Click to see full answer. Beside this, is lymphocytic infiltrate dangerous?Prognosis is good because lymphocytic infiltration of the skin may resolve spontaneously. Lymphocytic infiltration of the skin (LIS) is not associated with increased mortality. The lesions are commonly asymptomatic, although some patients report burning or pruritus.Furthermore, what causes Jessner’s lymphocytic infiltrate? The cause of Jessner lymphocytic infiltrate is unknown. It is classified as a benign T-cell lymphoproliferative disorder. Some cases have been associated with Borrelia infection, the cause of Lyme disease. Consequently, what is skin infiltration? From Wikipedia, the free encyclopedia. Infiltration is the diffusion or accumulation (in a tissue or cells) of foreign substances or in amounts in excess of the normal. The material collected in those tissues or cells is called infiltrate.What is atypical lymphoid infiltrate?Atypical lymphoid proliferations (AtLP) are conditions in which it is not possible to differentiate between the benign and the malignant nature of a given lymphoid infiltrate. AtLP are not necessarily premalignant and may very well represent a fully benign situation mimicking malignancy.