The George Beadle and Edward Tatum experiment proved that genes are responsible for making enzymes that control metabolic processes. From there, they determined that the mold needed the amino acid arginine, and their mutation was to a single gene that could encode for the enzyme that could produce it.Click to see full answer. Similarly, it is asked, what did George Beadle discover?George Wells Beadle (October 22, 1903 – June 9, 1989) was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells.One may also ask, who has given one gene one enzyme theory? George Beadle Likewise, people ask, what organism did Beadle and Tatum work with? Neurospora crassa What did Beadle and Tatum do to these organisms to produce genetic changes?In what became a celebrated experiment, Beadle and Tatum first irradiated a large number of Neurospora, and thereby produced some organisms with mutant genes. They then crossed these potential mutants with non-irradiated Neurospora. Normal products of this sexual recombination could multiply in a simple growth medium.